| 1. | Historically, silent mutations were thought to be of little to no significance.
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| 2. | Conversely, silent mutations are mutations in which the amino acid sequence is not altered.
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| 3. | Group 81A has chosen to develop the article Silent mutations.
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| 4. | Recent research suggests that silent mutations can have an effect on subsequent protein structure and activity.
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| 5. | There are several SNPs, found through NCBI GeneView, that cause missense or silent mutations in MEGF8.
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| 6. | Silent mutations affect protein folding and function.
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| 7. | Silent mutations may also affect transcriptional control.
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| 8. | Silent mutations can also be produced by insertions or deletions, which cause a shift in the reading frame.
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| 9. | Still, some believe that even silent mutations can cause significant behavioral phenotypes, and result in major phase changes.
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| 10. | Second, " silent mutations " may alter the DNA sequence of a gene without altering the encoded amino acids.
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